Our 134 Comprehensive Cancer Gene Panel

North Central Florida Diagnostics & DNA Technologies (NCF DNA) is one of a few high-complexity molecular diagnostics laboratories in the Continental United States. We’re a certified minority-owned business and accredited by the Joint Commission and CLIA. Unlike traditional laboratories that screen up to 30 cancer genes, we offer a comprehensive, inherited cancer panel that screens for 134 high-risk cancer genes. This revolutionary NextGen Sequencing™ technology yields highly accurate results within two weeks, verses traditional lab tests that could take up to 30 days. This advanced technology determines which gene mutations are pathogenic (cause cancer) and which are not. It focuses on targeted gene sequencing which helps us to remain at the forefront of precision medicine.

The 134 cancer gene panel screens for cancer susceptibility genes that may contribute to an individual’s risk of developing certain types of cancer such as breast, ovarian, lung, skin, stomach, colorectal, endometrial, pancreatic, renal, bladder, cervical bone, prostate and leukemia; to name some of the most common forms. In addition, we offer three separate cancer panels that specifically screen for breast and ovarian cancer (as a combined panel), colorectal and prostate cancer. Many of the genes in our panel have autosomal dominant inheritance for breast, ovarian, prostate, gastrointestinal and uterine cancers. With autosomal dominant inheritance, a single altered copy of the gene is sufficient to increase a person’ chances of developing cancer.

We use advanced technology that allows oncologists to intervene, early on, and map personalized treatment plans for their patients.

Our comprehensive panel detects if the patient has a mutation placing them at risk for cancer. Anyone with a family of history of cancer before the age of 60 or if an individual has been diagnosed, the test is covered by most insurances, which include Medicaid and Medicare. If there is an early onset of cancer in your family, then you should be tested for these very high risk cancer genes.

Mutations (pathogenic or likely pathogenic) are inherited from parents and passed on to the children. Initially, carriers could appear normal; however, they can pass on these genetic mutations to their children. According to research, our environment and some food sources have numerous cancer-causing agents. These carcinogens (chemicals/compounds) could damage the normal gene copy in carriers. For example, when intestinal cells divide in carriers there’s an increased chance for spontaneous mutation, which leads to polyp formation or even colon cancer. Nevertheless, there are several early screening tools to detect cancer such as mammograms, colonoscopies and annual checkups.

The benefits of using NCF DNA revolutionary DNA tests and laboratory include:

  • Accredited CLIA and Joint Commission
  • Early detection and monitoring
  • Highly accurate results within 15 days
  • Most comprehensive molecular analysis available
  • Most value for healthcare dollars

Our team of experts include molecular biologists, scientists, researchers and accessioners who pride themselves on delivering excellence with every patient sample.

We also offer three sub-panels that screen for the most common forms of cancer:

Brovanetics™ - screens for breast as well as ovarian cancer
Colonetics™ - screens for colon cancer
Pronetics™ - screens for prostate cancer


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